mono-ADP-ribosylation

mono-ADP-ribosylation is a common post-translational modification, where an ADP-ribose moiety is transferred from NAD⁺ to the substrate protein under the release of nicotinamide. The transfer of ADP-ribose occurs onto amino acid residues with a nucleophilic oxygen, nitrogen or sulfur. Lit.



Type
Incomplete
pKa1
None
pKa2
None
pKa3
None
NativeCharge
Loss
H
Gain
C15H22N5O13P2
Deltamass
Monoisotopic
541.061109016092
Average
541.301097661249
UVSpec
Display
λ
/ nm
ε
/ M-1 cm-1
214 20262
240 7836
245 11336
250 14962
255 17675
260 17751
265 15951
270 11843
272 9814
274 7963
276 6238
278 5046
280 3550
282 2612
284 1877
286 1268
288 888
290 558
292 279
294 228
296 127
298 76
300 0
302 0
304 0
306 0
308 0
310 0
312 0
314 0
316 0
318 0
320 0
H
AA
R, K, N, C, Q, S, T, D, E
Pattern