Hydroxyproline is produced by hydroxylation of the amino acid proline by the enzyme prolyl hydroxylase following protein synthesis (as a post-translational modification). Hydroxyproline is a major component of the protein collagen and plays a key roles for collagen stability. The sequence of collagen often follows the pattern Gly-Xaa-Hyp.



Type
Predefined
pKa1
None
pKa2
None
pKa3
None
NativeCharge
Loss
Gain
O
Deltamass
Monoisotopic
15.9949146195616
Average
15.999404927276
UVSpec
λ
/ nm 		ε
/ M-1 cm-1
214 0
240 0
245 0
250 0
255 0
260 0
265 0
270 0
272 0
274 0
276 0
278 0
280 0
282 0
284 0
286 0
288 0
290 0
292 0
294 0
296 0
298 0
300 0
302 0
304 0
306 0
308 0
310 0
312 0
314 0
316 0
318 0
320 0
H
AA
P
Pattern
(?<=G.)P