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{"id":307,"date":"2016-07-12T13:05:42","date_gmt":"2016-07-12T11:05:42","guid":{"rendered":"https:\/\/www.protpi.ch\/blog\/?p=307"},"modified":"2016-07-21T21:25:22","modified_gmt":"2016-07-21T19:25:22","slug":"mass-spectrometry-imaging-software-quantinetix","status":"publish","type":"post","link":"https:\/\/www.protpi.ch\/blog\/bioinformatics\/2016\/07\/mass-spectrometry-imaging-software-quantinetix\/","title":{"rendered":"A mass spectrometry imaging software: Quantinetix\u2122"},"content":{"rendered":"<figure id=\"attachment_314\" aria-describedby=\"caption-attachment-314\" style=\"width: 300px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-314 size-medium\" src=\"https:\/\/www.protpi.ch\/blog\/wp-content\/uploads\/2016\/07\/ThermoMS-300x155.png\" alt=\"ThermoMS\" width=\"300\" height=\"155\" srcset=\"https:\/\/www.protpi.ch\/blog\/wp-content\/uploads\/2016\/07\/ThermoMS-300x155.png 300w, https:\/\/www.protpi.ch\/blog\/wp-content\/uploads\/2016\/07\/ThermoMS-768x396.png 768w, https:\/\/www.protpi.ch\/blog\/wp-content\/uploads\/2016\/07\/ThermoMS-1024x528.png 1024w, https:\/\/www.protpi.ch\/blog\/wp-content\/uploads\/2016\/07\/ThermoMS-50x26.png 50w, https:\/\/www.protpi.ch\/blog\/wp-content\/uploads\/2016\/07\/ThermoMS.png 1400w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-314\" class=\"wp-caption-text\">Thermo&#8217;s Orbitrap LTQ MS\/MS data input.<\/figcaption><\/figure>\n<p>ImaBiotech, founded in 2009 by a team of experts, offers new molecular imaging (called MALDI imaging) services and products to life science industries. This new technology is capable of visualizing and quantifying biological compounds that play role in many pathologies like Cancer, Alzheimer or Parkinson diseases. It is also an interesting tool to follow new drug candidate into the body in all type theapeutics areas: dermatology, ophthalmology, toxicology, respiratory&#8230; This technology is capable of studying the role of biomolecules such as proteins, peptides, lipids, drugs, and metabolites and helps to understand their role in in different organs like the brain, liver or heart.<!--more--><\/p>\n<h3>Advantages of Quantinetix\u2122<\/h3>\n<p>The MALDI imaging\u00a0technique combines a number of advantages unlike any other approach (sensitivity, fast and quantitative).<\/p>\n<figure id=\"attachment_315\" aria-describedby=\"caption-attachment-315\" style=\"width: 300px\" class=\"wp-caption alignleft\"><a href=\"https:\/\/www.youtube.com\/watch?v=jEWtjR7KUUs\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-315 size-medium\" src=\"https:\/\/www.protpi.ch\/blog\/wp-content\/uploads\/2016\/07\/Convolution-300x163.png\" alt=\"MALDI imaging of an eyeball\" width=\"300\" height=\"163\" srcset=\"https:\/\/www.protpi.ch\/blog\/wp-content\/uploads\/2016\/07\/Convolution-300x163.png 300w, https:\/\/www.protpi.ch\/blog\/wp-content\/uploads\/2016\/07\/Convolution-768x417.png 768w, https:\/\/www.protpi.ch\/blog\/wp-content\/uploads\/2016\/07\/Convolution-1024x556.png 1024w, https:\/\/www.protpi.ch\/blog\/wp-content\/uploads\/2016\/07\/Convolution-50x27.png 50w, https:\/\/www.protpi.ch\/blog\/wp-content\/uploads\/2016\/07\/Convolution.png 1917w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><figcaption id=\"caption-attachment-315\" class=\"wp-caption-text\">Show normalized image with nice smoothing effect &#8211; Each area could be clairly identify<\/figcaption><\/figure>\n<p>Quantinetix\u2122, a software created by our team, with a patented technique is\u00a0 capable of interpreting and analysing molecules and drugs.\u00a0 This process is now used in preclinical and clinical studies to support scientist and doctor to better understanding diseases and to deliver new efficient medicines.<\/p>\n<h3>Key features of Quantinetix\u2122:<\/h3>\n<ul>\n<li>Quantinetix\u2122 is a quantitative imaging mass spectrometry software that provides quantification of target compounds.<\/li>\n<li>It is a user-friendly imaging program that offers normalization to get \u201creal images\u201d and provides concentration of your target compounds over histological regions in MSI datasets.\n<figure id=\"attachment_316\" aria-describedby=\"caption-attachment-316\" style=\"width: 300px\" class=\"wp-caption alignright\"><a href=\"http:\/\/www.maldi-msi.org\/download\/QuantinetixV2.pdf\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-316 size-medium\" src=\"https:\/\/www.protpi.ch\/blog\/wp-content\/uploads\/2016\/07\/AB-Sciex-300x154.png\" alt=\"AB-Sciex\" width=\"300\" height=\"154\" srcset=\"https:\/\/www.protpi.ch\/blog\/wp-content\/uploads\/2016\/07\/AB-Sciex-300x154.png 300w, https:\/\/www.protpi.ch\/blog\/wp-content\/uploads\/2016\/07\/AB-Sciex-768x393.png 768w, https:\/\/www.protpi.ch\/blog\/wp-content\/uploads\/2016\/07\/AB-Sciex-1024x524.png 1024w, https:\/\/www.protpi.ch\/blog\/wp-content\/uploads\/2016\/07\/AB-Sciex-50x26.png 50w, https:\/\/www.protpi.ch\/blog\/wp-content\/uploads\/2016\/07\/AB-Sciex.png 1400w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><figcaption id=\"caption-attachment-316\" class=\"wp-caption-text\">AbSciex&#8217;s 4800 MALDI TOF-TOF data input<\/figcaption><\/figure>\n<p>&nbsp;<\/li>\n<li>Quantinetix\u2122 normalizes and quantifies molecules in several ways: on-tissue dilution, isotopic labeling compound (normalization per position) or ion suppression calculation (<a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S1874391912005659\">Hamm et al., Journal of proteomics Sept 2012, normalization per ROI<\/a>)<\/li>\n<li>Quantinetix\u2122 is a multi-format software for different vendors format (Bruker, Sciex, Thermo, Waters). More technical infos on: <a href=\"http:\/\/www.maldi-msi.org\/download\/QuantinetixV2.pdf\">http:\/\/www.maldi-msi.org\/download\/QuantinetixV2.pdf<\/a><\/li>\n<\/ul>\n<h3>Further informations<\/h3>\n<p><iframe loading=\"lazy\" title=\"Quantinetix\u2122 Overview\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/jEWtjR7KUUs?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe><\/p>\n<p>To Discover our <strong>publication<\/strong>: <a href=\"https:\/\/www.imabiotech.com\/Quantinetix-Accelerates\"><span style=\"color: #0066cc;\">Quantinetix\u2122accelerates integration treatment of Quantitative MSI Data<\/span><\/a><\/p>\n<p>[ratings]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>ImaBiotech, founded in 2009 by a team of experts, offers new molecular imaging (called MALDI imaging) services and products to life science industries. This new technology is capable of visualizing and quantifying biological compounds that play role in many pathologies like Cancer, Alzheimer or Parkinson diseases. It is also an interesting tool to follow new [&hellip;]<\/p>\n","protected":false},"author":9,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[26],"tags":[29,9,27,28],"class_list":["post-307","post","type-post","status-publish","format-standard","hentry","category-bioinformatics","tag-imaging","tag-maldi","tag-mass-spectrometry","tag-software"],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/www.protpi.ch\/blog\/wp-json\/wp\/v2\/posts\/307","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.protpi.ch\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.protpi.ch\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.protpi.ch\/blog\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/www.protpi.ch\/blog\/wp-json\/wp\/v2\/comments?post=307"}],"version-history":[{"count":17,"href":"https:\/\/www.protpi.ch\/blog\/wp-json\/wp\/v2\/posts\/307\/revisions"}],"predecessor-version":[{"id":329,"href":"https:\/\/www.protpi.ch\/blog\/wp-json\/wp\/v2\/posts\/307\/revisions\/329"}],"wp:attachment":[{"href":"https:\/\/www.protpi.ch\/blog\/wp-json\/wp\/v2\/media?parent=307"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.protpi.ch\/blog\/wp-json\/wp\/v2\/categories?post=307"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.protpi.ch\/blog\/wp-json\/wp\/v2\/tags?post=307"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}