Prenylation

Prenylation covers two post-translational modifications in which one or two isoprenoid moieties, either farnesyl or geranylgeranyl moieties, are attached to a conserved cysteine residue via thioether bond at or near the C-terminus. Most prenylated proteins contain a CAAX motif at the C-terminus. The CAAX motif is a sequence of four amino acids, where “C” stands […]