Fast ultra-high resolution mass spectrum simulation with Prot pi version 2.1

Version 2.1 of the Protein Tool comes with a completely new software architecture. Even ultra-high resolution (up to 1’000’000) mass spectra of large proteins can now be simulated within sub-seconds. To get the mass spectrum, Prot pi calculates the accurate isotopic distribution using isotope-frequencies and mass defects of the chemical elements. Also the overall calculation time […]

Molecular mass and isoelectric point calculator for glycosylated proteins

Glycosylations should not be neglected for the correct calculation of the molecular mass, the isoelectric point and the mass-specific UV absorption coefficient. Therefore Prot pi provides a tool to draw glycans as a posttranslational modification of proteins. This short guide deals with how to add two complex-type N-Glycosylation G1 with a sialic acid (N-acetylneuraminic acid) […]

Isoelectric point calculation of native proteins

The isoelectric point (pI) of native (not denaturated) proteins is important in several separation techniques. The pI is defined as the pH value at which the positive and negative charges on the protein are balanced and the net charge is zero. To determine the pH at which the net charge is zero, the charge on […]

Encrypted data transfer enabled on Prot pi

To protect your valuable data, Prot pi is now reachable via HTTPS with secure sockets layer (SSL) encryption. Therefore the domain was migrated to a server with a static IP address and a security certificate was issued. The reason for this is to keep your sensitive information sent across the internet encrypted so that […]

Prot pi (Alpha) ist online

Vielen Dank für Ihren Besuch auf! Die erste Alphaversion der Bioinformatik-Plattform Prot pi ging am 11. Oktober 2014 Online. Prot pi ist ein Tool zur Berechnung physiko-chemischer Parameter von Proteinen anhand derer Aminosäure-Sequenz. Mit der aktuellen Alphaversion wird hauptsächlich die Stabilität der Programmierung überprüft. Das Release einer Betaversion mit erweiterter Funktionalität ist anfangs 2015 […]