Amidation is one of the most common post-translational modification in which the C-terminal carboxyl group is replaced by an amide group​1–5​. Amidation plays an important role in peptidesand peptide hormones. More than half of all mammalian peptide hormones and more than 80 % of all insect hormones have amidated C-termini​1​. The mechanism of amidation is […]